Plot UMAP side-by-side for biomarker and viability

Creates a side-by-side comparison of biomarker expression and predicted viability in UMAP space. Useful for visualizing correlation between marker and response.

Usage

plot_tsne_biomarker_viability(
  tsne_data,
  biomarker_var = "biomarker_scaled",
  viability_var = "viability_scaled",
  biomarker_label = "Biomarker Exp",
  viability_label = "Drug Viability",
  nrow = 1,
  base_size = 8
)

Arguments

tsne_data

Data frame with X, Y coordinates and both biomarker/viability columns.

biomarker_var

Character. Column name for biomarker expression. Default = "biomarker_scaled".

viability_var

Character. Column name for viability values. Default = "viability_scaled".

biomarker_label

Character. Legend label for biomarker. Default = "Biomarker Exp".

viability_label

Character. Legend label for viability. Default = "Drug Viability".

nrow

Integer. Number of rows in arrangement. Default = 1.

base_size

Numeric. Base font size. Default = 8.

Value

A gtable object from grid.arrange.

Examples

if (FALSE) { # \dontrun{
  tsne_data <- data.frame(
    X = lung_tSNE$X,
    Y = lung_tSNE$Y,
    biomarker_scaled = range01(rank(MDM2_expression)),
    viability_scaled = range01(rank(-viability_pred))
  )
  plot_tsne_biomarker_viability(tsne_data)
} # }