Calculates weighted average of clone-level expression to produce a pseudo-bulk expression profile for a single patient. This is used for evaluating model performance on pseudo-bulk data, not for prediction.
Usage
each_patient_pseudo_bulk(
x = 1,
comb_viability_df,
Clone_Counts_per_patients,
clone_Level_z_expression_df
)Arguments
- x
Integer. Index of the patient. Default = 1.
- comb_viability_df
Data frame. Retained for backward compatibility; no longer used (clone ids are read from the expression column names).
- Clone_Counts_per_patients
Data frame. Patient-clone abundance data.
- clone_Level_z_expression_df
Matrix. Clone-level expression data with columns named by patient-clone identifiers.